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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 7, No. 1, 2007, pp. 14-17
Bioline Code: hs07004
Full paper language: English
Document type: Research Article
Document available free of charge

African Health Sciences, Vol. 7, No. 1, 2007, pp. 14-17

 en Botulinum Toxin Treatment for Anal Fissure
Radwan, Mohamed M.; Ramdan, Khalil; Abu-Azab, Ismail & Abu-Zidan, Fikri M.


Objectives: To evaluate the effectiveness of Botulinum toxin injection in the treatment of anal fissure.
Methods: 38 patients (22 males, 16 females; mean age (SD) of 33.3 (8.3) years) who have presented to Surgical Outpatient Clinic at Al Ain Hospital, United Arab Emirates, with anal fissure in the period between June 2000 and September 2001 and treated with Botulinum toxin injection were retrospectively studied.They were followed up for at least 8 weeks to evaluate the effects of treatment.
Results: Treatment with Botulinum toxin was effective in 89% of patients with chronic uncomplicated anal fissure.Two patients experienced minor incontinence in the form of a fecal soiling which disappeared later.
Conclusion: Botulinum toxin injection is an effective alternative for surgery for treatment of uncomplicated idiopathic anal fissure. Surgery should be offered to patients who do not improve with Botulinum toxin injection and to those with complicated anal fissure.

Anal fissure, chronic, botulinum toxin, sphincterotomy.

© Copyright 2007 - Makerere Medical School, Uganda

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