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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 11, No. s1, 2011, pp. S112-S116
Bioline Code: hs11067
Full paper language: English
Document type: Research Article
Document available free of charge

African Health Sciences, Vol. 11, No. s1, 2011, pp. S112-S116

 en Pulmonary involvement of Brucellosis: a report of six cases
Simsek, F; Yildirmak, MT; Gedik, H; Kantürk, A & Iris, EN


Background: Pulmonary involvement of brucellosis rarely occurs due to inhalation of infected aerosol or hematogenous overspreading.
Objective The study aimed to reveal the pulmonary manifestations of brucellosis that occur rarely in Brucella infections in the context of six cases in this report.
Methods: Between 1998-2008, 82 patients with brucellosis treated and followed up at infectious diseases clinic have been retrospectively studied in relation to their clinical and laboratory findings and treatment results.
Results: Patients’ (n=6) age ranged from 48 to 59 years and they showed equal gender distribution. All patients presented with fever and cough. Radiological examination showed pneumonic patches and consolidation in two cases, bilateral glass round opacity in four cases, perivascular and peribronchial thickness increase in two cases, pleural effusion in two cases, sentri-acinar emphysematous images in one patient, and athelectasis in one patient. Blood cultures of three patients grew Brucella check for this species in other resources spp. . All patients responded to treatment containing doxycycline, rifampicin and streptomycin (for only one patient) within seven to 10 days and were treated for six weeks except for one patient for who was treated eight weeks due to hepatosplenic brucellosis.
Conclusion: Pulmonary involvement of brucellosis has good prognosis with combined antimicrobial therapy.

Brucellosis, pulmonary, manifestations

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