African Health Sciences
Makerere University Medical School
Vol. 19, No. 4, 2019, pp. 3200-3207
Bioline Code: hs19189
Full paper language: English
Document type: Study
Document available free of charge
African Health Sciences, Vol. 19, No. 4, 2019, pp. 3200-3207
© Copyright 2019 - Govender et al.
An overview of Pneumocystis jirovecii pneumonia for the African generalist practitioner|
Govender, I; Maphasha, OM; Rangiah, S & Steyn, C
Introduction: Pneumocystis jirovecii is the causative organism of Pneumocystis pneumonia (PCP) in humans, which is more common among immunocompromised patients. Classically patients present with fever, non-productive cough, and dyspnoea. In the HIV-infected individuals the symptoms may be subtle at first, but gradually progress over several weeks. In the HIV-uninfected patient, however, the duration of symptoms is shorter and more severe, mainly due to the increased inflammatory response of the HIV-uninfected patient.
Methods: This article focuses on the diagnostic methods and then the management and prophylaxis principles of PCP by reviewing the best current practices and guidelines in Africa.
Conclusion: This overview is presented by clinicians who have experience with PCP and is directed mainly at first-line healthcare providers.
Pneumocystis jirovecii pneumonia; african generalist practitioner.