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Indian Journal of Surgery
Medknow Publications on behalf of Association of Surgeons of India
ISSN: 0972-2068
Vol. 65, No. 4, 2003, pp. 354-360
Bioline Code: is03070
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Surgery, Vol. 65, No. 4, 2003, pp. 354-360

 en Review Article - Limb salvage for malignant primary bone tumours: current status with a review of the literature
Manish G. Agarwal, Ajay Puri


Though primary malignant bone tumours form only about 1% of all cancers, their aggressive natural history makes disease control very difficult. Effective chemotherapy has improved survival and advances in imaging, engineering and surgical techniques have made limb salvage feasible and the world has moved from amputation to limb salvage in the majority of cases with non-metastatic disease at presentation. Indigenously developed technology and chemotherapy protocols have allowed our own results to be comparable to those reported in the Western literature. Newer biomaterials and fabrication methods have allowed us to develop indigenously a high-quality yet affordable customized megaprosthesis which forms the backbone of limb salvage surgery. This paper broadly reviews the literature and presents our own experience with the current limb salvage methods as carried out at the Tata Memorial Hospital.

Limb salvage, Endoprosthesis, Megaprosthesis, Rotationplasty, Osteosarcoma, Ewing's sarcoma, Biopsy, Neoadjuvant chemotherapy

© Copyright 2003 Indian Journal of Surgery. Online full text also at

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