Indian Journal of Surgery
Medknow Publications on behalf of Association of Surgeons of India
Vol. 66, No. 3, 2004, pp. 156-159
Bioline Code: is04038
Full paper language: English
Document type: Research Article
Document available free of charge
Indian Journal of Surgery, Vol. 66, No. 3, 2004, pp. 156-159
© Copyright 2004 Indian Journal of Surgery.
Role of methylprednisolone in acute cervical cord injuries|
Rasool Tahir , Wani MA, Kirmani Altaf R, Ramzan Altaf U, Wani Rauf Ahmad , Imtiyaz Syed , Batool Gilani Z
BACKGROUND: Management of acute cervical cord injury with neurodeficit continues to evoke debate. Glucocorticoid steroid methylprednisolone has been found to be effective in preventing secondary cord injury. Aims: This study was done to evaluate the role of methylprednisolone in acute cervical cord injury.
MATERIAL AND METHODS: Thirty patients of acute cervical cord injury with demonstrable neurological deficit were administered methylprednisolone within 8 hours of acute cervical cord injury while eighteen others were not administered this drug. The patients were assessed for neurological recovery.
RESULTS: Patients who received methylprednisolone within 8 hours of injury had more motor recovery (P<0.001) than those who were not given the drug. Improvement in the pinprick scores and light touch scores were also greater at 6 weeks (P<0.001). Similar effect was also seen after 6 months.
CONCLUSION: Methylprednisolone prevents secondary cord injury to a great extent and hence its administration in the immediate post injury period results in a better functional (motor and sensory) outcome
Methylprednisolone sodium succinate, Cervical cord injuries, Neurodeficit