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Journal of Postgraduate Medicine
Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India
ISSN: 0022-3859 EISSN: 0022-3859
Vol. 57, No. 4, 2011, pp. 307-313
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Bioline Code: jp11087
Full paper language: English
Document type: Review Article
Document available free of charge
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Journal of Postgraduate Medicine, Vol. 57, No. 4, 2011, pp. 307-313
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Tuberculosis and female reproductive health
Ghosh, K; Ghosh, K & Chowdhury, J R.
Abstract
Tuberculosis (TB) is an important cause of mortality and morbidity all over the world and is particularly relevant in developing countries like India where the disease is endemic. Female reproductive system is very vulnerable to this infection and clinical presentation of this disease in female reproductive tract is protean in nature and in a large majority of patients could be completely silent. This disease is an important cause of infertility, menstrual irregularity, pregnancy loss, and in association with pregnancy, morbidity to both the mother and child increases. Some of the effects of TB infection on female genital tract could be remote in nature due to infection elsewhere. Medicines used to treat TB infection can also have adverse effects on contraception and other areas of female reproductive health. HIV coinfection and multidrug-resistant tuberculosis (MDR-TB) and increased population migration from developed to developing countries have now added a whole new dimension to this infection. Though new, finer diagnostic tools of detection of TB are increasingly available in the form of bacterial cultures and polymerase chain reaction (PCR) based diagnostics, suspicion by clinicians remains the main tool for diagnosis of the condition. Hence, doctors need to be properly trained to become "Tuberculosis Minded".
Keywords
Endometritis, fetal loss, human immunodeficiency virus infection, hormonal imbalance, menorrhagia, multidrug-resistant tuberculosis, synecheae, tuberculosis
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