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Case Repot - Role of CSF serology in follow-up of subacute Sclerosing Panencephalitis patients on treatment Gupta E, Dar L, Singh S, Behari M, Broor S Abstract Subacute sclerosing panencephalitis (SSPE) is a progressive inflammatory disease of the central nervous system with poor prognosis and high mortality. No effective treatment has a proven role; oral isoprinosine and intrathecal administration of α-interferon may prolong survival. We report an unusual case of adult onset SSPE patient on treatment with significant clinical improvement, even in the absence of conversion to seronegativity in either CSF or serum, on follow-up serological examination. Keywords Subacute sclerosing panencephalitis, CSF serology, follow up.

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