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African Journal of Biomedical Research
Ibadan Biomedical Communications Group
ISSN: 1119-5096
Vol. 4, No. 3, 2001, pp. 161-163
Bioline Code: md01074
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Biomedical Research, Vol. 4, No. 3, 2001, pp. 161-163

 en Short Communication - THE ASSESSMENT OF FASCIOLA GIGANTICA INFECTION IN THE RABBIT (ORYCTOLAGUS CUNICULUS) AS A LABORATORY MODEL PARASITE DEVELOPMENT - CLINICAL SYMPTOMS AND LIVER PATHOLOGY
ADEDOKUN, O. A and FAGBEMI, B. O.

Abstract

In this study, the rabbit was assessed as a laboratory host for the helminthes parasite, Fasciola gigantica check for this species in other resources . Three groups of rabbits were Infected experimentally with 5, 10 end 15 metacercariae of F. gigantica respectively. Clinical signs found included pale mucous membrane, progressive emaciation and rough hair coat. The post mortem findings Included haemorrhage and scattered calcified nodules on the omentum. Echymosis. fibrosis and necrosis were prominent on (he Ever in addition to fibrosis and thickening of the gall bladder and bife ducts. Histopathology of the Ever revealed congestion. haemorrhage, ceffular Infiltration end necrosis, BE. ducts were hyper plastic and fibrotic with sever Inflammatory reactions. The ova of gigantica were recovered from the faeces of some infected rabbits at 10 weeks post infection. Mean number of flukes recovered from the rabbits was 0 in the 5 metacercariae group, 2 in the 10 metacercariae group and 5 in the group given 15 metacercariae.

Keywords
Fasciola gigantica , fascioliasis, rabbit, laboratory model. Fascioliasis in rabbitst

 
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