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Middle East Fertility Society Journal
Middle East Fertility Society
ISSN: 1110-5690
Vol. 11, No. 1, 2006, pp. 48-52
Bioline Code: mf06008
Full paper language: English
Document type: Research Article
Document available free of charge

Middle East Fertility Society Journal, Vol. 11, No. 1, 2006, pp. 48-52

 en Diclofenac for analgesia in assisted conception: a prospective cohort study*
Mashael Al Deery, Kamal Jaroudi,Saad Al Hassan,Rima Bazzi, Abdulaziz Al Shahrani, Khalid Awartani,


Objective: To assess the effectiveness of diclofenac in pain experience following oocyte retrieval under conscious sedation. Setting: Assisted reproductive unit (ART) in a tertiary care referral centre.
Design: Prospective controlled non-randomized study.
Materials and Methods: One hundred and thirty six infertility patients undergoing IVF or ICSI treatment where included. All patients received pre-ovum pickup (OPU) conscious sedation in form of alfentanil 0.5 mg IV, in addition the treatment group (n=81) received 100 mg diclofenac per rectal 30 minutes pre OPU, the control group (n=55) had no pre OPU diclofenac.
Main outcome Measures: Pain score measurement performed at 30 minutes, one, two, and 12 hours post OPU.
Results: Average pain score in the treatment group was significantly lower than that of the control group at each measured time interval.
Conclusion(s): Pre OPU Diclofenac is an effective medication for reducing post procedure pain experience.

Analgesia, ART, Diclofenac, IVF

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