REVIEW- Biological and reproductive implications of stem cell research and therapeutics: prospects in the Middle East

Objective: To explore the potential ways in which stem cell research is linked to research and clinical aspects of Obstetrics and Gynecology practice. Moreover, to explore the possible applications most tailored to the needs and resources of the Middle East.
Design: Medical and biological databases were searched for references to stem cells.
Summary: Stem cells are undifferentiated cells that are capable of self-renewal and differentiation to more specialized cells. The discovery of different sources of stem cells enhanced research in this field substantially. Obstetrics and Gynecology is likely to have many points of intersection and cross talk with stem cell research either as a source or as a benefactor. Stem cell research could offer various solutions to gynecological tumors, perinatal pathologies, infertility management and placental development studies. The source of stem cells is mostly dependant on obstetrical-related supplies. Therefore, obstetricians and gynecologists should be aware of the significance of this research to their practice. This review is a aimed at exploring the possibilities of building a basis for stem cell research in the Middle East, with special emphasis on cultural and ethical issues, and resources in the area.

Keywords
stem cell, stem cell markers, embryonic stem cells, umbilical cord stem cells, fetal stem cells, trophoblast stem cells, ovarian tumors, endometrial cancer, infertility, endometriosis, perinatal, epigenetic, progenitors.