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Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
ISSN: 1394-195X
Vol. 9, No. 1, 2002, pp. 3-8
Bioline Code: mj02002
Full paper language: English
Document type: Research Article
Document available free of charge

Malaysian Journal of Medical Sciences, Vol. 9, No. 1, 2002, pp. 3-8

 en REVIEW ARTICLE - C-Fos and Its Consequences in Pain
Asma Hayati Ahmad & Zalina Ismail


The discovery that c-fos, a proto-oncogene, has a role in pain, has triggered extensive research on the consequences of c-fos expression. It has been shown that c-fos, through its protein form, FOS, leads to expression of dynorphin gene and subsequently dynorphin protein which is implicated in the development of a pain state. This mini review looks at the properties of c-fos and the consequences of its expression following noxious (painful) stimulation.

c-fos, pain, dynorphin

© Copyright 2002 - Malaysian Journal of Medical Science
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