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Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
ISSN: 1394-195X
Vol. 16, No. 4, 2009, pp. 73-76
Bioline Code: mj09037
Full paper language: English
Document type: Case Report
Document available free of charge

Malaysian Journal of Medical Sciences, Vol. 16, No. 4, 2009, pp. 73-76

 en Acute tonsillitis with concurrent Kikuchi’s Disease as a cause of persistent lymphadenopathy
Sawali, Halimuddin; Athar, Primuharsa Putra Sabir Husin; Ami, Mazita; Shamsudin, Nor Hasni & Nair, Gopalan


We present a young adult female with symptoms of acute tonsillitis and tender cervical lymphadenopathy. Despite a full course of oral antibiotics, she had persistent left lower cervical lymphadenopathy measuring 2.0 x 1.5 cm at 2 weeks post-treatment. Rigid and flexible scope examinations did not reveal any abnormalities in the nasopharynx, oropharynx or hypopharynx. Tuberculosis tests were negative and blood index results were normal. Fine needle aspiration cytology revealed a non-specific granulomatous inflammatory process. Excisional lymph node biopsy was performed, and the patient was diagnosed as having Kikuchi’s Disease (KD). We would like to highlight the diagnostic challenges in detecting this condition and the importance of differentiating KD from tuberculosis and malignant lymphoma, the latter of which requires aggressive treatment.

histiocytic necrotizing lymphadenitis, Kikuchi disease, Kikuchi-Fujimoto disease, medical sciences

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