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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 51, No. 3, 2003, pp. 350-354
Bioline Code: ni03114
Full paper language: English
Document type: Research Article
Document available free of charge

Neurology India, Vol. 51, No. 3, 2003, pp. 350-354

 en Effect of mannitol in experimental spinal cord injury: An ultrastructural and electrophysiological study
Baysefer A, Erdogan E, Kahraman S, Izci Y, Korkmaz C, Solmaz I, Ulas UH, Ozogul C, Timurkaynak E


rauma was induced; and those in Group III received the same amount of 0,9% NaCl in the same manner. Preoperative and postoperative SSEP records at the end of 2 weeks were obtained. Electron microscopy examination of the cord samples was done at 2 weeks postoperatively. Statistical Analysis used: Fischer's Exact Test. Results: SSEP records, ultrastructural findings and clinical recovery showed that minor neural damage and significant recovery occurred in Group II. Conclusion: This study demonstrates that the administration of 2 g/kg of 20% mannitol produces significant improvement in the neural structures and protects the spinal cord following injury.

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