Medknow Publications on behalf of the Neurological Society of India
Vol. 54, No. 1, 2006, pp. 75-77
Bioline Code: ni06020
Full paper language: English
Document type: Research Article
Document available free of charge
Neurology India, Vol. 54, No. 1, 2006, pp. 75-77
© Copyright 2006 Neurology India.
Brief Report - Neuropsychiatric manifestations systemic lupus erythematosus: A study from South India|
Robert M, Sunitha R, Thulaseedharan NK
Context: Neuropsychiatric systemic lupus erythematosus (NPSLE) has varied manifestations.
Aims: To study the pattern of neuropsychiatric (NP) involvement in systemic lupus erythematosus (SLE).
Settings and Design: Hospital based cross sectional and retrospective study.
Patients and Methods: Patients admitted with a diagnosis of SLE, during a period of 16 months, were evaluated and any NP syndrome present classified as per the American College of Rheumatology (ACR) nomenclature.
Statistical analysis: SPSS software Version 10 was used for descriptive analysis and correlative study.
Results: Out of 50 patients with SLE, all the patients with NPSLE [39 (78%)] were females, mean age 25.66 years (range: 11-44). The commonest manifestation was headache [20 (55.6%)]. Seizures were seen in 8 (20.51%) and psychosis in 6 (16.2%). Fine distal tremor was seen in 8 (20.51%) of patients.
Conclusions: Headache is a frequent NP syndrome. Fine distal tremor is a syndrome not included in ACR classification but seen is 20% of our patients with NPSLE.
Neurolupus, neuropsychiatric syndromes, neuropsychiatric systemic lupus erythematosus, systemic lupus erythematosus.
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