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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 57, No. 2, 2009, pp. 203-205
Bioline Code: ni09058
Full paper language: English
Document type: Case Report
Document available free of charge

Neurology India, Vol. 57, No. 2, 2009, pp. 203-205

 en Adult medulloblastoma mimicking Lhermitte-Duclos disease: Can diffusion weighted imaging help?
Mittal, Puneet; Gupta, Kamini; Saggar, Kavita & Kaur, Supreet


Lhermitte-Duclos disease, also known as dysplastic cerebellar gangliocytoma, is a rare cerebellar benign tumor with characteristic appearance of thickened cerebellar folia giving a laminated or striated appearance, quite diagnostic of the condition. We had seen a patient with medulloblastoma with imaging findings suspicious for thickened cerebellar folia reminiscent of Lhermitte-Duclos disease. However, it showed patchy contrast enhancement and restricted diffusion on diffusion-weighted imaging, which are not typically associated with Lhermitte-Duclos disease. Presence of restricted diffusion proved to be a useful diagnostic feature for differentiation between the two lesions. This patient highlights the importance of obtaining all the MR imaging sequences in suspected Lhermitte-Duclos disease and histological diagnosis if there is doubt.

Diffusion, folia, gangliocytoma, Lhermitte-Duclos, medulloblastoma

© Copyright 2009 Neurology India.
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