Eleutherine bulbosa check for this species in other resources - fungicide - medicinal plant - Cladosporium sphaerospermum check for this species in other resources "/>
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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 98, No. 5, 2003, pp. 709-712
Bioline Code: oc03145
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 98, No. 5, 2003, pp. 709-712

 en Eleutherinone, a Novel Fungitoxic Naphthoquinone from Eleutherine bulbosa check for this species in other resources (Iridaceae)
Tânia Maria Almeida Alves; Helmut Kloos & Carlos Leomar Zani

Abstract

The dichloromethane extract prepared from the underground parts of Eleutherine bulbosa check for this species in other resources (Miller) Urban (Iridaceae) showed strong activity in the direct bioautography assay with the phytopathogenic fungus Cladosporium sphaerospermum check for this species in other resources . This assay was used to guide the fractionation of this extract and allowed the isolation of four compounds: the new naphthoquinone eleutherinone [8-methoxy-1-methyl-1,3-dihydro-naphtho(2,3-c)furan-4,9 -dione] and the known compounds, previously isolated from this species, eleutherin [9-methoxy-1(R),3(S)-dimethyl-3,4-dihydro-1H-benzo(g)isochromene-5,10-dione], isoeleutherin [9-methoxy-1(R),3(R)-dimethyl-3,4-dihydro-1H-benzo(g)isochromene-5,10-dione], and eleutherol [4-hydroxy-5-methoxy-3(R)-methyl-3H-naphtho(2,3-c)furan-1 -one]. All quinonoid compounds showed strong antifungal activity in the bioautography assay at 100 μg/spot, while eleutherol was inactive.

Keywords
naphthoquinone - Eleutherine bulbosa check for this species in other resources - fungicide - medicinal plant - Cladosporium sphaerospermum check for this species in other resources

 
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