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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 102, No. 1, 2007, pp. 111-115
Bioline Code: oc07019
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 102, No. 1, 2007, pp. 111-115

 en Impairment of cell division of Trypanosoma cruzi check for this species in other resources epimastigotes
Zacks, Michele A

Abstract

The mechanisms that facilitate the adaptation of Trypanosoma cruzi check for this species in other resources to two distinct hosts, insect and vertebrate, are poorly understood, in part due to the limited ability to perform gene disruption studies by homologous recombination. This report describes a developmentally-defective phenotype that resulted from integration of a drug marker adjacent to the GAPDH gene in T. cruzi.

Keywords
Trypanosoma cruzi - life cycle - differentiation

 
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