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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060 EISSN: 1678-8060
Vol. 105, No. 4, 2010, pp. 467-470
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Bioline Code: oc10080
Full paper language: English
Document type: Research Article
Document available free of charge
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Memórias do Instituto Oswaldo Cruz, Vol. 105, No. 4, 2010, pp. 467-470
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Schistosoma mansoni : magnetic resonance analysis of liver fibrosis according to WHO patterns for ultrasound assessment of schistosomiasis-related morbidity
Silva, Luciana C.S.; Andrade, Luciene M.; de Queiroz, Leonardo C.; Voieta, Izabela; Azeredo, Letícia M.; Antunes, Carlos M.F. & Lambertucci, José R.
Abstract
For the last two decades, ultrasound (US) has been considered a surrogate for the gold standard in the
evaluation of liver fibrosis in schistosomiasis. The use of magnetic resonance imaging (MRI) is not yet standardised for
diagnosing and grading liver schistosomal fibrosis. The aim of this paper was to analyse MRI using an adaptation
of World Health Organization (WHO) patterns for US assessment of schistosomiasis-related morbidity. US and MRI
were independently performed in 60 patients (42.1 ± 13.4 years old), including 37 men and 23 women with
schistosomiasis. Liver involvement appraised by US and MRI was classified according to the WHO protocol from patterns
A-F. Agreement between image methods was evaluated by kappa index (k). The correlation between US and MRI
was poor using WHO patterns [k = 0.14; confidence interval (CI) 0.02; 0.26]. Even after grouping image patterns as
“A-D”, “Dc-E” and “Ec-F”, the correlation between US and MRI remained weak (k = 0.39; CI 0.21; 0.58). The
magnetic resonance adaptation used in our study did not confirm US classification of WHO patterns for liver fibrosis.
Keywords
schistosomiasis - ultrasound - magnetic resonance - WHO patterns - hepatic fibrosis
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