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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 106, No. s1, 2011, pp. 159-166
Bioline Code: oc11153
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 106, No. s1, 2011, pp. 159-166

 en Chemoresistance of Plasmodium falciparum check for this species in other resources and Plasmodium vivax check for this species in other resources parasites in Brazil: consequences on disease morbidity and control
Gama, Bianca Ervatti; Lacerda, Marcus Vinicius Guimarães; Daniel-Ribeiro, Cláudio Tadeu & Ferreira-da-Cruz, Maria de Fátima

Abstract

In Brazil, malaria still remains a clinically important febrile syndrome for local populations and travelers, occurring mostly in the Amazon Basin. This review aims to report the main efforts employed to control this disease since the 1940s and the emergence of Plasmodium falciparum check for this species in other resources and Plasmodium vivax check for this species in other resources chemoresistance to chloroquine and sulphadoxine-pyrimethamine among other drugs. Additionally, in vivo, in vitro and molecular studies as well as malaria chemoresistance consequences on disease morbidity and policy treatment guidelines were commented.

Keywords
Plasmodium falciparum, Plasmodium vivax, malaria, chemoresistance, Brazil

 
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