Brazilian Journal of Oral Sciences
Piracicaba Dental School - UNICAMP
Vol. 7, No. 24, 2008, pp. 1512-1519
Bioline Code: os08009
Full paper language: English
Document type: Research Article
Document available free of charge
Brazilian Journal of Oral Sciences, Vol. 7, No. 24, 2008, pp. 1512-1519
© Copyright 2008 - Piracicaba Dental School - UNICAMP São Paulo - Brazil
Comparison of rat bone healing following intra-alveolar grafting with organic or inorganic bovine bone particles|
Calixto, Romeu Felipe Elias; Teófilo, Juliana Mazzonetto; Brentegani, Luiz Guilherme & Lamano, Teresa
This study compared, histometrically, the alveolar bone healing
after grafting rats extraction socket with particles of organic or inorganic
The volume fraction of grafted materials and bone trabeculae
was estimated in histologic images at the end of the 2nd and 9th weeks
post-operatively by a differential point-counting method.
Particles of both materials were observed partially filling
the cervical alveolar third and the volume fraction of inorganic graft
was larger than that of organic graft 2 and 9 weeks following
implantation. Although evoking neither a foreign-body reaction nor a
persisting inflammatory response, both materials delayed bone healing.
By the 2nd week, the delay was more pronounced in the animals
grafted with inorganic than in those grafted with organic bone, but
only in the animals whose inorganic graft occupied more than 50% of
the cervical third. By the 9th week, despite the greater volume fraction
of inorganic graft the percent of bone healing was similar to that
observed in the animals grafted with organic bone.
The degree of impairment of bone healing resulted from
combination of factors such as type of material, its relative amount
and the phase of the reparational process.
organic bovine bone graft, inorganic bovine bone graft, alveolar healing
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