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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-9827
Vol. 7, No. 2, 2008, pp. 975-979
Bioline Code: pr08016
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 7, No. 2, 2008, pp. 975-979

 en Antifungal activity of Erigeron floribundus check for this species in other resources (Asteraceae) from Côte d'Ivoire, West Africa
Bi, F.H. Tra; Koné, M.W. & Kouamé, N.F.

Abstract

Purpose: Erigeron floribundus check for this species in other resources is a reputed medicinal plant used in Côte d'Ivoire, West Africa for the treatment of skin disorders. The aim of this study was to evaluate the antifungal activity of this plant against fungi from human origin.
Method: Dichloromethane, methanol 80% and aqueous extracts from the leaves with stem were tested for their antifungal activity against 7 strains of dermatophytes ( Epidermophyton floccosum check for this species in other resources , Microsporum canis check for this species in other resources , M. gypseum, M. langeronii, Trichophyton mentagrophytes check for this species in other resources , T. rubrum, T. soudanense ) and one strain of the filamentous fungus, check for this species in other resources . The assays were performed using the agar dilution method at serial concentrations ranging from 2 to 0.06 mg/ml.
Result: Only the dichloromethane extract exhibited an activity against Microsporum canis and a broad spectrum of good antifungal activity against all the remaining fungi tested.
Conclusion: To the best our knowledge, this is the first report of the antifungal activity of Erigeron floribundus against a wide range of dermatophytes, including Microsporum langeronii check for this species in other resources and Trichophyton soudanense check for this species in other resources , the most frequent dermatophytes in Côte d'Ivoire. E. floribundus might be potential sources for improved traditional medicines or new antidermatophyte agents for the treatment of dermatomycoses.

Keywords
Erigeron floribundus, dermatophytes, antifungal activity, Côte d'Ivoire.

 
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