Purpose:
The purpose of this investigation was to isolate novel flavonoids from
Alpinia
galanga
rhizomes.
Methods:
The methanol extract of
Alpinia galanga was subjected to column chromatography and
eluted with ethyl acetate-methanol (9:1) to yield a compound, galangoflavonoside (AG 11). The structure
of the compound was elucidated by various spectral techniques (UV, IR,
1H NMR,
13C NMR, and MS).
Results:
Chemical investigation of the extract furnished a new flavonoid galangoflavonoside (AG 11).
Conclusion:
The isolated compound, galangoflavonoside (AG 11,) could be a potential therapeutic
compound as well as serve as a lead compound in the synthesis of other useful flavonoids. Isolation of
the galangoflavonoside from Alpinia galanga rhizomes is being reported, to the best of our knowledge,
for the first time.
