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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-9827
Vol. 8, No. 6, 2009, pp. 545-550
Bioline Code: pr09070
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 8, No. 6, 2009, pp. 545-550

 en Galangoflavonoid Isolated from Rhizome of Alpinia galanga check for this species in other resources (L) Sw (Zingiberaceae)
Jaju, S.B.; Indurwade, N.H.; Sakarkar, D.M.; Fuloria, N.K.; Ali, M.D.; Das, S. & Basu, S.P.

Abstract

Purpose: The purpose of this investigation was to isolate novel flavonoids from Alpinia galanga check for this species in other resources rhizomes.
Methods: The methanol extract of Alpinia galanga was subjected to column chromatography and eluted with ethyl acetate-methanol (9:1) to yield a compound, galangoflavonoside (AG 11). The structure of the compound was elucidated by various spectral techniques (UV, IR, 1H NMR, 13C NMR, and MS).
Results: Chemical investigation of the extract furnished a new flavonoid galangoflavonoside (AG 11).
Conclusion: The isolated compound, galangoflavonoside (AG 11,) could be a potential therapeutic compound as well as serve as a lead compound in the synthesis of other useful flavonoids. Isolation of the galangoflavonoside from Alpinia galanga rhizomes is being reported, to the best of our knowledge, for the first time.

Keywords
Alpinia galangal; Methanol extract; Galangoflavonoside; Spectral techniques

 
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