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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-9827
Vol. 10, No. 3, 2011, pp. 335-340
Bioline Code: pr11043
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 10, No. 3, 2011, pp. 335-340

 en Evaluation of the Antibacterial Activity of 14 Medicinal Plants in Côte d’Ivoire
Bolou, GEK; Bagré, I; Ouattara, K & Djaman, AJ

Abstract

Purpose: To evaluate the antibacterial potentials of fourteen ethnobotanically selected plants traditionally used in different parts of Côte d’Ivoire for the treatment of typhoid fever and gastrointestinal disorders.
Method: The antimicrobial activity of the extracts of the plant was tested against a collection strain of Salmonella typhimurium, a clinical strain of Salmonella typhi check for this species in other resources and Pseudomonas aeruginosa check for this species in other resources by macrobroth dilution method. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined.
Results: All the plants had bactericidal activity against at least one of the test microorganisms with both MIC and MBC ranging from 2.5 to > 80 mg/ml. Among the plant extracts, Terminalia glaucescens check for this species in other resources . (Combretaceae) Bersama abyssinica subsp. paullinioides check for this species in other resources (Melianthaceae ) and Abrus precatorius check for this species in other resources (Fabaceae) showed the most promising broad spectrum antibacterial properties, inhibiting all of the strains tested, especially S. Typhi and P. aeruginosa, with MBC ranging from 2.5 to 5 mg/ml.
Conclusion: The findings provide support for the use of these plants in traditional medicine for treatment of typhoid fever and gastrointestinal disorders, and are thus, potential sources of drugs that would need to be subjected to further studies.

Keywords
Antimicrobial activity, Ivorian medicinal plants, MIC, MBC

 
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