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Iranian Journal of Pharmacology and Therapeutics
Razi Institute for Drug Research (RIDR) of Iran University of Medical Sciences and Health Services (IUMS)
ISSN: 1735-2657
Vol. 5, No. 1, 2006, pp. 21-25
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Bioline Code: pt06003
Full paper language: English
Document type: Research Article
Document available free of charge
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Iranian Journal of Pharmacology and Therapeutics, Vol. 5, No. 1, 2006, pp. 21-25
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Effect of Aqueous Extract of Leaf of Aegle marmelos  on Testicular Activities in Rats
Das, Uttam Kumar; Maiti, Rajkumar; Jana, Debasis & Ghosh, Debidas
Abstract
The aqueous extract of leaf of Aegle marmelos (Bael) at the dose 50 mg/100 g body weight resulted a significant diminution in the activities of key testicular steroidogenic enzymes along with low levels of plasma testosterone and relative wet weights of sex organs in respect to control without any significant alteration in general body growth. Germ cells numbers in different generation at stage VII of seminiferous epithelial cell cycle were diminished significantly after the treatment of the above extract. The above mentioned dose did not exhibit any toxicity in liver and kidney. Therefore, it may be predicted that the aqueous extract of leaf of Aegle marmelos has a potent antitesticular effect at a specific dose.
Keywords
Aegle marmelos, Steroidogenic key enzymes, Plasma testosterone, Germ cells
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© Copyright 2006 - Razi Institute for Drug Research (RIDR)
Alternative site location: http://ijpt.iums.ac.ir/
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