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Iranian Journal of Pharmacology and Therapeutics
Razi Institute for Drug Research (RIDR) of Iran University of Medical Sciences and Health Services (IUMS)
ISSN: 1735-2657
Vol. 5, No. 2, 2006, pp. 121-126
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Bioline Code: pt06020
Full paper language: English
Document type: Research Article
Document available free of charge
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Iranian Journal of Pharmacology and Therapeutics, Vol. 5, No. 2, 2006, pp. 121-126
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The Relationship among Glycemic, Small Intestinal Transit and Insulinemic States in Normal Mice
REDDY, PEDDYREDDY MURALI KRISHNA
Abstract
in levels and SIT was observed in 36 group. At a lower doses of dextrose administration (0.4 and 1 g/kg) no association of BG with SIT was seen, but, when the dose was increased by 4 g/kg an inverse relationship observed with SIT. Similarly with the lower doses of dextrose no association between insulinemic state and SIT was observed. But, when the dose of dextrose increased to 4 g/kg an inverse relationship between serum insulin levels and SIT was observed. It can be concluded from this study that a fall in BG levels or serum insulin levels favours attenuation of SIT from 6-30 h of food deprivation. Normal to moderate glycemic or insulinemic states have no influence on SIT.
Keywords
Blood glucose level, Dextrose, Diabetes mellitus, Food deprivation, Serum insulin level, Small Intestinal Transit
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© Copyright 2006 - Razi Institute for Drug Research (RIDR)
Alternative site location: http://ijpt.iums.ac.ir/
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