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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 3, No. 1, 2006, pp. 36-43
Bioline Code: tc06004
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 3, No. 1, 2006, pp. 36-43

 en ANTIDIABETIC AND HYPOLIPIDEMIC EFFECTS OF LAPORTEA OVALIFOLIA check for this species in other resources (URTICACEAE) IN ALLOXAN INDUCED DIABETIC RATS.
Claudia E. N. MOMO , Julius. E. OBEN , Dagobert TAZOO, Etienne DONGO

Abstract

Laportea ovalifolia check for this species in other resources (Scham and Thonn) is widly use in Cameroon for the treatment of diabetes mellitus. The present study was designed to evaluate the antidiabetic and hypolipidaemic effects of aqueous extract of Laportea ovalifolia aerial part in normal and alloxan diabetic rats. Diabetes was induced by intraperitoneal injection of alloxan (150 mg kg –1 body weight). The treatment was given for 2 weeks. After the treatment a significant reduction was observed in fasting serum glucose levels in the treated diabetics rats. L. ovalifolia treatment showed considerable lowering of serum total cholesterol, triglycerides, LDL cholesterol, T.C/HDL.C and an increase in HDL cholesterol in the treated diabetic group. These results suggest that the Laportea ovalifolia aqueous extract of the aerial part possesses antidiabetic and hypolipideamic effects in alloxan-induced diabetic rats.

Keywords
Laportea ovalifolia, Alloxan, antidiabetic , hypolipidemic

 
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