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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 5, No. 3, 2008, pp. 271-277
Bioline Code: tc08039
Full paper language: English
Document type: Review Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 5, No. 3, 2008, pp. 271-277

 en A Pilot Study On The Effect Of Catha edulis check for this species in other resources Frosk., (Celastraceae) On Metabolic Syndrome In Wokw Rats
Mahmood, Samira Abdulla & Lindequist, Ulrike

Abstract

This study investigated the effect of Catha edulis check for this species in other resources (khat) on some important parameters of the metabolic syndrome in Wistar Ottawa Karlsburg W (WOKW ) rat. The animals were fed with the standard chow containing 5% air dried pulverized khat leaves for 14 days; followed by the standard chow for16 days. The khat leaves were sorted into green (khat light; KL) and crimson (khat dark; KD) leaves. The control rats were fed on standard chow. Blood glucose (G), serum insulin, serum leptin and serum lipids (triglycerides, total cholesterol, HDL-, LDL-, and VLDL cholesterol) were determined. Feeding with khat leaves reduced the body weight and the triglyceride level of the animals. The effect of KD on these parameters was stronger than that of KL. KD lowered the blood glucose concentration and the leptin content whereas KL was inactive. The khat intake had no significant influence on serum insulin, total serum cholesterol, HDL-, LDL- and VLDL-cholesterol.

Keywords
Catha edulis, WOKW rats, metabolic syndrome

 
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