search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 6, No. 4, 2009, pp. 518 - 525
Bioline Code: tc09041
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 6, No. 4, 2009, pp. 518 - 525

 en Phytochemical And Antimicrobial Studies Of Four Species Of Cola Schott & Endl. (Sterculiaceae)
Sonibare, Mubo Adeola; Soladoye, Micheal O.; Esan, Oyedokun O. & Sonibare, Oluwadayo O.

Abstract

The in-vitro antimicrobial evaluation of ethanol extracts of four species of Cola Schott & Endl. was done using human isolated strains of Staphylococcus aureus check for this species in other resources , Staphylococcus albus check for this species in other resources , Bacillus subtilis check for this species in other resources , Klebsiella pneumonia check for this species in other resources , Pseudomonas aeruginosa check for this species in other resources , Candida albicans check for this species in other resources , Aspergillus niger check for this species in other resources as test organisms. The assays were carried out by agar well diffusion, erythromycin and ketoconazole served as the control drugs. The leaf ethanol extracts of the plants were found to be more effective against the tested fungi than the bacteria at high concentrations. None of the extracts was active against Staphylococcus aureus. Plant extract of C. acuminata (P. Beauv.) Schott & Endl. and C. nitida (Vent) Schott & Endl. showed activity on S. albus at concentrations ranging from 10-150 mgml-1 having comparable diameters of zone of inhibition of 7.3±0.03-16.0±0.0 for C. acuminata and 10.0±0.0-19.0±0.0 for C. nitida. Also, these two species of Cola demonstrated activities on C. albicans and A. niger at concentrations ranging from 90-150mgml-1 with relatively close diameters of zone of inhibition. Only C. acuminata inhibited the growth of K. pneumoniae at the MIC of 90mgml-1 whereas, C. albicans was inhibited by C. acuminata, C. millenii K. Schum and C. gigantea A.Chev. at the MIC of 120mgml-1. Phytochemical screening of the four species of Cola showed the presence of alkaloids, saponins, tannins and cardenolides in all the plants which apart from showing the probable closeness of the species could also be responsible for the observed activities. The antimicrobial property shown by the plant extracts is an evidence of the ethnomedicinal uses of the plants. The similarity observed in the phytochemical constituents and antimicrobial activities demonstrated by C nitida (Vent.) Schott & Endl., C. millenii and C.gigantea A. Chev. and C. acuminata suggest a probable closeness among these species. The results obtained in this study provide preliminary evidence of the chemotaxonomic significance of secondary metabolites and antimicrobial activities in infra-generic taxonomy of species of Cola.

Keywords
Cola species, Sterculiaceae, phytochemical screening, antimicrobial studies, taxonomy.

 
© Copyright 2009 - African Journal Traditional, Complementary and Alternative Medicines
Alternative site location: http://journals.sfu.ca/africanem/index.php/ajtcam

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2017, Site last up-dated on 05-Dec-2017.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil