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Zoological Research
Kunming Institute of Zoology, Chinese Academy of Sciences
ISSN: 2095-8137
Vol. 41, No. 4, 2020, pp. 365-372
Bioline Code: zr20039
Full paper language: English
Document type: Review Article
Document available free of charge

Zoological Research, Vol. 41, No. 4, 2020, pp. 365-372

 en Physiological and pathological insights into exosomes in the brain
Li, Xiao-Hui; Zhang, Juan; Li, Ding-Feng; Wu, Wei; Xie, Zhong-Wen & Liu, Qiang

Abstract

Exosomes are small vesicles secreted by all cell types in the brain and play a role in cell-cell communication through the transfer of cargo or encapsulation. Exosomes in the brain have considerable impact on neuronal development, activation, and regeneration. In addition, exosomes are reported to be involved in the onset and propagation of various neurodegenerative diseases. In this review, we discuss the content of exosomes derived from major cell types in the brain, and their function under physiological and pathological conditions.

Keywords
Exosomes; Brain; Neurodegenerative diseases; Cell-cell communication

 
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