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Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
ISSN: 1018-4406
EISSN: 1018-4406
Vol. 16, No. 1, 2006, pp. 82-87
Bioline Code: pe06013
Full paper language: Farsi
Document type: Research Article
Document available free of charge

Iranian Journal of Pediatrics, Vol. 16, No. 1, 2006, pp. 82-87

 en Intractable seizure in a case with parry-Romberg syndrome and good response to intravenous immune globulin
Ashrafzadeh, F & Farajirad, M.


Objective: Parry-Romberg syndrome is a rare disorder associated with unilateral facial atrophy involving skin, subcutaneous tissue, skeletal muscles and bone. Occasionally, there is central nervous system involvement with epilepsy being the most common manifestation.
Case report: In this article, we report a 12 year-old boy with Parry-Romberg syndrome. He had seizures since he was 5 years old, since 1 year ago the seizure attacks were refractory in spite of taking several antiepileptic drugs. Significant improvement was obtained after administration of intravenous immune-globulin (IVIG).
Conclusion: IVIG may be of benefit when seizures in Parry-Romberg syndrome are intractable and resistant to antiepileptic drugs.

parry Romberg syndrome , Intractable Epilepsy , Intravenous Immune globulin , Scleroderma , seizure

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