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Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
ISSN: 1018-4406
EISSN: 1018-4406
Vol. 20, No. 1, 2010, pp. 58-62
Bioline Code: pe10007
Full paper language: English
Document type: Research Article
Document available free of charge

Iranian Journal of Pediatrics, Vol. 20, No. 1, 2010, pp. 58-62

 en Reinfection Rate after Successful Helicobacter pylori check for this species in other resources Eradication in Children
Najafi, Mehri; Sobhani, Mohammad; Khodadad, Ahmad; Farahmand, Fatemeh & Motamed, Farzaneh


Objective: Reinfection rate of Helicobacter pylori check for this species in other resources after successful eradication is low in developed countries. This study was performed to determine the reinfection rate of H. pylori during a follow up period of 12 months in Iranian children.
Methods: In this prospective study, children with H. pylori infection were treated with triple omeprazole based regimen. Patients with negative 13C urea breath test (UBT) performed after 8 weeks of therapy, were followed up by the same test after 1 year.
Findings: Thirty seven patients, aged 5 to 17 years, were studied. Among them 25 (67.5 %) were boys. After eradication therapy of H. pylori, 34 patients had negative 13C UBT. Reinfection occurred in 5 (14.7 %) patients. Reappearance or continuing symptoms after treatment were associated with higher rate of recurrence (P=0.042).
Conclusion: Recurrence rate of H. pylori was high in our children. Successful eradication significantly decreased complaints and further symptoms. Follow up and reevaluation of patients is necessary especially when there are symptoms after eradication.

Helicobacter Pylori; Gastritis; Peptic Ulcer; Breath Test; Furazolidone; Omeprazole

© © 2010 by Center of Excellence for Pediatrics, Children’s Medical Center, Tehran University of Medical Sciences,All rights reserved.
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