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Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
ISSN: 1018-4406
EISSN: 1018-4406
Vol. 24, No. 2, 2014, pp. 191-197
Bioline Code: pe14034
Full paper language: English
Document type: Research Article
Document available free of charge

Iranian Journal of Pediatrics, Vol. 24, No. 2, 2014, pp. 191-197

 en Risk Factors of Germinal Matrix Intraventricular Hemorrhage in Premature Infants
Pekcevik, Yeliz; Pasinli, Aynur; Ozer, Esra Arun & Erdogan, Nuri


Objective: To determine whether some clinical parameters can be used to predict the hemorrhage and whether the relationship between these clinical variables and the grades of hemorrhage is linear.
Methods: A total of 230 premature infants, born at a gestational age less than 34 weeks were retrospectively reviewed. Germinal matrix-intraventricular hemorrhage (GM-IVH), the grade of the hemorrhage, and clinical data were assessed with a checklist. Variables were analyzed by using Mann Whitney U and Fisher\'s exact tests and then multiple logistic regression analysis was used to evaluate the independent risk factors.
Findings: Resuscitation, gestational age, hypotension, multiple birth, and birth weight were found to be independent risk factors. We determined non-linear relationship between the grades of hemorrhage and the clinical parameters. But when we classified hemorrhages as grade 1, grade 2-3 and grade 4, the relationships were found linear.
Conclusion: Premature infants who had resuscitation, low gestational age, hypotension, multiple birth, and low birth weight are more likely to have GM-IVH. The relationship between the clinical variables and the grades of GM-IVH does not seem to be linear.

Ultrasonography; Risk Factors; Premature Infants; Hemorrhage; Germinal Matrix

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