Purpose: To isolate and characterize chemical compounds of biological importance from the whole
plant of
S. scariosa
.
Methods: The whole plant of
Sunipia scariosa was extracted with methanol (MeOH) and
chromatographed on silica gel and sephadex LH-20 to afford the pure isolates. High perfomance liquild
chromatography (HPLC) was used for further purification of the isolated compounds. Characterization of
the isolated compounds was achieved by 1H and 13C nuclear magnetic resonance spectroscopy
(NMR) and mass spectrometry (MS).
Results: Batatasin III (3,3’-dihydroxy-5-methoxybibenzyl) and 3,4’-dihydroxy-5-methoxybibenzyl, a pair
of positional isomers, were isolated from the whole plant of
Sunipia scariosa. The yields of the two
isomers were 60 and 40 %, respectively, from the mixture of two compounds.
Conclusion: Batatasin III and 3,4’-dihydroxy-5-methoxybibenzyl, a pair of positional isomers were
successfully isolated from the whole plant of
Sunipia scariosa for the first time.
