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Rwanda Medical Journal
Rwanda Health Communication Center - Rwanda Biomedical Center (RHCC - RBC)
ISSN: 2079-097X
EISSN: 2079-097X
Vol. 79, No. 1, 2022, pp. 50-56
Bioline Code: rw22007
Full paper language: English
Document type: Research Article
Document available free of charge

Rwanda Medical Journal, Vol. 79, No. 1, 2022, pp. 50-56

 en Prevalence and outcome of bacterial meningitis among children of less than 10 years along the Kilombero valley in Morogoro, Tanzania
Madoshi, P. B.; Sanga, Z. E.; Ngarawa, K. A. N. & Lubomba, W.


INTRODUCTION: Bacterial meningitis is among the febrile, lethal and life-threatening diseases in neonates and children under 10 years, especially in low-income countries. The study determined the prevalence and outcome of the disease among neonates, infants and children less than 10 years admitted at St. Francis Referral Hospital.
METHODS: A hospital-based study was carried out among 856 children less than ten years, with or without fever for 10 months; clinical and laboratory records were reviewed. Data analysis was done using Chi-square and independent t-test to establish the odds ratio of acquiring the disease.
RESULTS: Out of 856 records of children with fever 656 had signs of meningitis, 71 children underwent lumbar puncture where 49.3% and 50.7% were female and male respectively; Aged 0-2 years (47.9%), 3 – 5 years (19.7%) and 6 – 10 years (32.4%). 62% of the patients had neurological signs, 56.3% had >45mmol/dl CSF (cerebrospinal fluid) glucose concentration and 85.9% had >50mg/dl of the CSF protein concentration. Escherichia coli check for this species in other resources , Klebsiella pneumoniae check for this species in other resources , Haemophilus influenzae check for this species in other resources and Neisseria meningitides check for this species in other resources were mostly isolated from the CSF samples at the hospital. Location (OR) = 3.1; p = 0.0017), parity of the mother (OR = 3.8; p = 0.008), Neurological signs (OR = 4.5; p = 0.001) and elevated CSF protein (OR = 4.5; p = 0.001) were the factors associated with bacterial meningitis infection among children.
CONCLUSION: Meningitis is a life-threatening infection in children under 10 years. Thus, microbial isolation should be established in most hospitals to improve early case identification and reporting at health facilities and the national level.

Meningitis; Escherichia coli; Neisseria spp; Under-Ten Children; Prevalence

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